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apoptosis
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Selected Featured Publications:

Yuval Shaked, Elizabeth Pham, Santosh Hariharan, Ksenia Magidey, Ofrat Beyar-Katz, Ping Xu, Shan Man, Florence T.H. Wu, Valeria Miller, David Andrews and Robert S. Kerbel

Evidence Implicating Immunological Host Effects in the Efficacy of Metronomic Low-Dose Chemotherapy

Cancer Research 2016 V16(20)

Abstract  Full Text  Adobe PDF

Sina Oppermann, Jarkko Ylanko, Yonghong Shi, Santosh Hariharan, Christopher C. Oakes, Patrick M. Brauer, Juan C. Zúñiga-Pflücker, Brian Leber, David E. Spaner, David W. Andrews

Identification of kinase inhibitors that overcome venetoclax resistance in activated CLL cells by high-content screening

Blood 2016

Abstract  Full Text  Adobe PDF

Anthony Tsikouras, Richard Berman, David W. Andrews, and Qiyin Fang

High-speed multifocal array scanning using refractive window tilting

Biomedical Optic Express, Vol 6, Issue 10, 2015

Abstract  Full Text  Adobe PDF

Collins Tony J., Ylanko Jarkko, Geng Fei, and Andrews David W.

A Versatile Cell Death Screening Assay Using Dye-Stained Cells and Multivariate Image Analysis

Assay and Drug Development Technologies, Vol 13, Issue 9, Sep 2015

Abstract  Full Text  Adobe PDF

Justin Kale, Qian Liu, Brian Leber, David W. Andrews

Shedding Light on Apoptosis at Subcellular Membranes

Cell December 2012, Volume 151 Issue 6 pp:1179-1184

Abstract  Full Text  Adobe PDF

Qian Liu, Brian Leber, David W. Andrews

Interactions of pro-apoptotic BH3 proteins with anti-apoptotic Bcl-2 family proteins measured in live MCF-7 cells using FLIM FRET

Cell Cycle October 2012, Volume 11 Issue 9 pp:3536-3542

Abstract  Full Text  Adobe PDF

Aranovich, A., Liu, Q., Collins, T.J., Geng F, Dixit S, Leber B. and David W. Andrews.

Differences in the mechanisms of proapoptotic BH3 proteins binding to Bcl-XL and Bcl-2 quantified in live MCF-7 cells

Mol Cell. March 2012 Vol-45 Issue-6 pp:754-763.

Abstract  Full Text  Adobe PDF

Anthony Tsikouras, Jin Ning, Sandy Ng, Richard Berman, D W Andrews and Qiyin Fang

Streak camera crosstalk reduction using a multiple delay optical fiber bundle

Optics Letters January 2012 Vol. 37, Issue 2, pp. 250-252


Abstract  Full Text  Adobe PDF

Glauber C Brito, D W Andrews

Removing Bias against membrane proteins in interaction networks

BMC Systems Biology October 2011 , 5:169


Full Text Adobe PDF

Domina Falcone, Matthew P. Henderson, Hendrik Nieuwland, Christine M. Coughlan, Jeffrey L. Brodsky and D W Andrews

Stability and function of the Sec61 translocation complex depends on the Sss1p tail-anchor sequence

Biochem Journal June 2011 Vol-436 Issue-2 pp-291-303


Abstract Full Text Adobe PDF

Christian Bogner, Leber, B. and David W. Andrews

Apoptosis: embedded in membranes

Current Opinion in Cell Biology Volume 22, Issue 6, December 2010, Pages 845–851

Abstract  Full Text  Adobe PDF

Ding, J., Zhang, Z., Roberts, J.G., Falcone, D., Miao, Y., Shao, Y., Zhang, X.C., David W. Andrews and Lin, J.

Bcl-2 and Bax Interact via the BH1–3 Groove-BH3 Motif Bcl-2 and Bax Interact via the BH1–3 Groove-BH4 Motif

The Journal of Biological Chemistry June 2010 285- 37 (28749–28763)

Abstract  Full Text  Adobe PDF


Jonathan F. Lovell, Lieven P. Billen, Scott Bindner, Aisha Shamas-Din, Cecile Fradin, Brian Leber, and David W. Andrews

Membrane Binding by tBid Initiates an Ordered Series of Events Culminating in Membrane Permeabilization by Bax .

Cell 135(6): 1074-1084, 04 December 2008


 Abstract Full Text Adobe PDF
 

Lieven P. Billen, Candis L. Kokoski, Jonathan F. Lovell, Brian Leber, David W. Andrews

Bcl-XL Inhibits Membrane Permeabilization by Competing with Bax

PLoS Biol 6(6): e147 doi:10.1371/journal.pbio.0060147


Primer Full Text Adobe PDF