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Publications: Cancer Research

Yuval Shaked, Elizabeth Pham, Santosh Hariharan, Ksenia Magidey, Ofrat Beyar-Katz, Ping Xu, Shan Man, Florence T.H. Wu, Valeria Miller, David Andrews and Robert S. Kerbel

Evidence Implicating Immunological Host Effects in the Efficacy of Metronomic Low-Dose Chemotherapy

Cancer Research 2016 V16(20)

Abstract  Full Text  Adobe PDF

Sina Oppermann, Avery J. Lam, Stephanie Tung, Yonghong Shi, Lindsay McCaw, Guizhei Wang, Jarkko Ylanko, Brian Leber, David Andrews, David E. Spaner

Janus and PI3-kinases mediate glucocorticoid resistance in activated chronic leukemia cells

Oncotarget 2016 V7(45)

Abstract  Full Text 

Sina Oppermann, Jarkko Ylanko, Yonghong Shi, Santosh Hariharan, Christopher C. Oakes, Patrick M. Brauer, Juan C. Zúñiga-Pflücker, Brian Leber, David E. Spaner, David W. Andrews

Identification of kinase inhibitors that overcome venetoclax resistance in activated CLL cells by high-content screening

Blood 2016

Abstract  Full Text  Adobe PDF

Brahmbhatt H, Oppermann S, Osterlund EJ, Leber B, Andrews DW

Molecular Pathways: Leveraging the BCL-2 Interactome to Kill Cancer Cells--Mitochondrial Outer Membrane Permeabilization and Beyond

Radiation Research Vol 21 Issue 12 Mar 2015


Abstract  Full Text  Adobe PDF

Mills CE, Thome C, Koff D, Andrews DW, Boreham DR

The relative biological effectiveness of low-dose mammography quality X rays in the human breast MCF-10A cell line

Radiation Research Vol 183 Issue 1 2015


Abstract  Full Text  Adobe PDF

Brian Leber,Fei Geng, Justin Kale and D W Andrews

Drugs targeting Bcl-2 family members as an emerging strategy in cancer

Expert Reviews in Molecular Medicine Vol 12 Dec 2010


Abstract  Full Text  Adobe PDF

M Firoz Mian, Nicole M Lauzon, D W Andrews, Brian D Lichty, Ali A Ashkar

FimH Can Directly Activate Human and Murine Natural Killer Cells via TLR4

Molecular Therapy 18, 1379-1388 (July 2010)


Abstract  Full Text  Adobe PDF

L P Billen, A Shamas-Din, D W Andrews

Bid: a Bax-like BH3 protein

Oncogene 27, S93-S104 (30 July 2009)


Abstract Full Text Adobe PDF

Le Lam; Xiuying Hu; Zackie Aktary; David W Andrews; Manijeh Pasdar.

Tamoxifen and ICI 182,780 increase Bcl-2 levels and inhibit growth of breast carcinoma cells by modulating PI3K/AKT, ERK and IGF-1R pathways independent of ER? .

Accepted Breast Cancer Research and Treatment November 11, 2008, 10.1007/s10549-008-0231-y


Abstract Full Text Adobe PDF

Xue, L-Y., Chiu, S-M., Fiebig, A., Andrews, D.W. and Oleinick, N. L.   

Photodamage to Multiple Bcl-xL Isoforms by Photodynamic Therapy with the Phthalocyanine Photosensitizer Pc 4.

Oncogene. 2003 Dec 18;22(58):9197-204.

Abstract Full Text Adobe PDF

Annis MG, Zamzami N, Zhu W, Penn LZ, Kroemer G, Leber B, Andrews DW.

Endoplasmic reticulum localized Bcl-2 prevents apoptosis when redistribution of cytochrome c is a late event.

Oncogene. 2001 Apr 12;20(16):1939-52.

Abstract Full Text Adobe PDF

Brenner, C., Cadiou, H., Vieira, H.L.A., Zamzami, N., Marzo, I., Xie, Z., Leber, B., Andrews, D.W., Duclohier, H., Reed, J.C., and Kroemer, G.

Bcl-2 and Bax regulate the channel activity of the mitochondrial adenine nucleotide translocator.

Oncogene. 2000 Jan 20;19(3):329-36  

Abstract Full Text Adobe PDF

Lee ST, Hoeflich KP, Wasfy GW, Woodgett JR, Leber B, Andrews DW, Hedley DW, Penn LZ.

Bcl-2 targeted to the endoplasmic reticulum can inhibit apoptosis induced by Myc but not etoposide in Rat-1 fibroblasts.

Oncogene. 1999 Jun 10;18(23):3520-8.  

Abstract Full Text Adobe PDF

Zhu W, Eicher A, Leber B, Andrews DW.

At the onset of transformation polyomavirus middle-T recruits shc and src to a perinuclear compartment coincident with condensation of endosomes.

Oncogene. 1998 Aug 6;17(5):565-76.  

Abstract Adobe PDF